This picture was taken from the west side of the canal bridge on Broadway, looking northeast. The photographer would have been standing near the Rippel building. The house was across from the Philadelphia & Reading passenger depot. The womens’ names are not known, but they appear to be mother and daughter. The picture was likely taken in the early 1880s, and the house may have been destroyed by fire, because it does not appear in later pictures. It appears on the map of 1884, but is gone by 1913. For a point of reference, look at the 1883 relief map here.
Notice the sign on the left, which has the name McCormick on it. This was the wallpaper store of James Hammond McCormick.
The picture below, taken in 1897, shows a better view of the house. The home of Jacob Gauger can be seen to the right.